Epigenetic Components of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Uncover Potential Transposable Element Activation
نویسندگان
چکیده
منابع مشابه
Chronic fatigue syndrome/myalgic encephalitis.
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متن کاملChronic fatigue syndrome or myalgic encephalomyelitis.
Chronic fatigue syndrome or myalgic encephalomyelitis (CFS/ME) is a debilitating illness that affects many systems of the body, particularly the nervous and immune systems. The condition affects all age, racial, ethnic and socioeconomic groups. This article focuses on the knowledge, understanding and skills necessary to recognise, assess, manage and support patients with CFS/ME. The principles ...
متن کاملEpigenetic regulation of transposable element derived human gene promoters.
It was previously thought that epigenetic histone modifications of mammalian transposable elements (TEs) serve primarily to defend the genome against deleterious effects associated with their activity. However, we recently showed that, genome-wide, human TEs can also be epigenetically modified in a manner consistent with their ability to regulate host genes. Here, we explore the ability of TE s...
متن کامل[Diagnosis and Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome].
We present here the Japanese clinical diagnostic criteria for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) that were proposed in 2016 by the Japanese Ministry of Health, Labour and Welfare study group. The clinical diagnosis criteria of ME/CFS were created to be used by healthcare agencies in charge of primary care practice. We also explain the current prognosis in ME/CFS and med...
متن کاملInvestigation of suspected chronic fatigue syndrome/myalgic encephalopathy.
BACKGROUND Chronic fatigue is a frequently occurring problem in both the primary and specialist health services. The Department of Neurology at Haukeland University Hospital has established a standard assessment for patients referred with suspected CFS/ME. This study reports diagnoses and findings upon assessment, and considers the benefit of supplementary examinations. MATERIAL AND METHOD Di...
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ژورنال
عنوان ژورنال: Clinical Therapeutics
سال: 2019
ISSN: 0149-2918
DOI: 10.1016/j.clinthera.2019.02.012